blood protein measurement blood tissue inhibitor of metalloproteinase-1 level 2019-02-15T15:26:13Z CMO:0003049 Measurement of the amount of tissue inhibitor of metalloproteinase 1 (TIMP-1)in a specific sample of blood. TIMP-1 belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. clinical_measurement_ontology sjwang