volume of distribution of nifedipine in the blood 2019-04-23T15:06:12Z CMO:0003141 In pharmacology, the volume of distribution (VD, also known as apparent volume of distribution) is the theoretical volume that would be necessary to contain the total amount of an administered drug at the same concentration that it is observed in the blood plasma. It is defined as the distribution of a medication between plasma and the rest of the body after oral or parenteral dosing. VT:0010622 apparent volume of distribution clinical_measurement_ontology sjwang blood nifedipine metabolism measurement