calculated blood vessel dilation force reduction measurement carbachol response/sensitivity measurement concentration of carbachol at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) 2020-05-12T17:18:33Z A calculated value for the concentration of carbachol, the ammonium salt that is a slowly hydrolyzed cholinergic agonist that acts at both muscarinic receptors and nicotinic receptors, at which the energy exerted during the active expansion in the diameter of a blood vessel in response to the application of carbachol is halfway between the highest value, that is the force at greatest constriction (often measured in a pre-constricted blood vessel), and the lowest achievable value of such contractile energy during carbachol-induced relaxation of the vessel wall (i.e. the maximum effect of carbachol which is the minimum contractile energy). CHEBI:3385 CMO:0003409 MESH:D002217 VT:0000197 clinical_measurement_ontology concentration of carbamylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) concentration of carbastat at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) slaulede