part of part of develops_from midgut caecum vermiform appendix A blind-ended tube connected to the cecum, from which it develops embryologically[WP]. A comparative anatomical approach reveals three apparent morphotypes of the cecal appendix, as well as appendix-like structures in some species that lack a true cecal appendix. Cladistic analyses indicate that the appendix has evolved independently at least twice (at least once in diprotodont marsupials and at least once in Euarchontoglires), shows a highly significant (P < 0.0001) phylogenetic signal in its distribution, and has been maintained in mammalian evolution for 80 million years or longer.[well established][VHOG] BTO:0000084 CALOHA:TS-1267 EFO:0000849 EHDAA2:0000588 EMAPA:35140 EV:0100076 EV:0100080 FMA:14542 GAID:308 MA:0001540 MAT:0000287 MESH:A03.492.411.495.209.290 MIAA:0000287 OpenCyc:Mx4rvVjGgJwpEbGdrcN5Y29ycA Organ with organ cavity which is continuous proximally with the cecum and distally terminates in the tip of the appendix. Examples: There is only one appendix[FMA:14542]. UBERON:0001154 UMLS:C0003617 VHOG:0001306 apex of caecum apex of cecum appendiceal appendix appendix vermiformis appendix vermiformis caecal appendix cecal appendix galen:AppendixVermiformis uberon vermix lower digestive tract digestive system element