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    <!-- http://purl.obolibrary.org/obo/CVDO_0000181 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CVDO_0000181">
        <rdfs:label xml:lang="en">disturbed anterograd blood flow through mitral valve during left ventricular diastole</rdfs:label>
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        <rdfs:label xml:lang="en">mitral valve disorder</rdfs:label>
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        <rdfs:label xml:lang="en">mitral valve narrowed opening during left ventricular diastole</rdfs:label>
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        <rdfs:label>mitral valve stenosis</rdfs:label>
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        <oboInOwl:hasDbXref>UMLS_CUI:C0026269</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>mitral valve stenosis</oboInOwl:hasExactSynonym>
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        <oboInOwl:hasDbXref>NCI:C50654</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>Mitral valve stenosis is a rheumatic disease of mitral valve characterized by the narrowing of the orifice of the mitral valve of the heart. Most cases of mitral stenosis are due to disease in the heart secondary to rheumatic fever and the consequent rheumatic heart disease. Less common causes of mitral stenosis are calcification of the mitral valve leaflets, and as a form of congenital heart disease. However, there are primary causes of mitral stenosis that emanate from a cleft mitral valve. Other causes include Bacterial endocarditis where the vegetations may favor increase risk of stenosis.</ns3:IAO_0000115>
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        <oboInOwl:hasExactSynonym>Mitral stenosis NOS</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Mitral stenosis</oboInOwl:hasExactSynonym>
        <ns3:CVDO_0000419 xml:lang="en">A disease in which some disorder of a mitral valve prevents it from opening properly during left ventricular diastole, occasioning disturbance in the anterograd blood flow through the valve.</ns3:CVDO_0000419>
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