realized in has material basis at all times has occurrent part aortic valve improper close during left ventricular diastole retrograd blood flow through aortic valve during left ventricular diastole aortic valve disorder aortic valve insufficiency Aortic valve regurgitation (disorder) SNOMEDCT_2010_1_31:60234000 DOID:57 MSH:D001022 NCI:C50861 NCI:C51223 aortic regurgitation A disease in which an abnormal structure in an aortic valve prevents it to close propertly during diastole, occasioning a retrograd blood flow through the valve. Aortic valve insufficiency is a aortic valve disease where leaking of the aortic valve of the heart causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle. Aortic insufficiency can be due to abnormalities of either the aortic valve or the aortic root (the beginning of the aorta). UMLS_CUI:C0003504 aortic insufficiency disease_ontology disease disease course