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        <rdfs:label>has major susceptibility factor</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_0050425 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_0050425">
        <rdfs:label xml:lang="en">restless legs syndrome</rdfs:label>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_610439"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_102300"/>
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        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004005"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_615197"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0004005"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_608831"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_611242"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_612853"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/MIM_611185"/>
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        </rdfs:subClassOf>
        <ns4:IAO_0000115 xml:lang="en">A central nervous system disease characterized by throbbing, pulling creeping or other unpleasant sensations in the legs and the irresistible urge to move them.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>ICD9CM:333.94</oboInOwl:hasDbXref>
        <oboInOwl:id>DOID:0050425</oboInOwl:id>
        <oboInOwl:hasDbXref>GARD:11926</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D012148</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2025_09_01:32914008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0035258</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C84501</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:PS102300</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:G25.81</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0004270</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">WED</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Willis-Ekbom disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Wittmaack-Ekbom syndrome</oboInOwl:hasExactSynonym>
        <rdfs:comment xml:lang="en">Xref MGI.</rdfs:comment>
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    <!-- http://purl.obolibrary.org/obo/DOID_331 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_331">
        <rdfs:label xml:lang="en">central nervous system disease</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/MIM_102300 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_102300">
        <rdfs:label>susceptibility to restless legs syndrome 1</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_608831 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_608831">
        <rdfs:label>susceptibility to restless legs syndrome 2</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_610438 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_610438">
        <rdfs:label>susceptibility to restless legs syndrome 3</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_610439 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_610439">
        <rdfs:label>susceptibility to restless legs syndrome 4</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_611185 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_611185">
        <rdfs:label>susceptibility to restless legs syndrome 6</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_611242 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_611242">
        <rdfs:label>susceptibility to restless legs syndrome 5</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_612853 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_612853">
        <rdfs:label>susceptibility to restless legs syndrome 7</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MIM_615197 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MIM_615197">
        <rdfs:label>susceptibility to restless legs syndrome 8</rdfs:label>
    </Class>
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