has phenotype has symptom disease has location tyrosinemia type II 2012-06-13T03:09:31Z A tyrosinemia that has_material_basis_in deficiency of hepatic tyrosine aminotransferase located_in the liver and is characterized by keratitis, painful palmoplantar hyperkeratosis, mental retardation, and elevated serum tyrosine levels. DOID:0050725 disease_ontology MIM:276600 Oculocutaneous tyrosinemia Richner-Hanhart syndrome skin disease liver disease amino acid metabolic disorder tyrosinemia Palmoplantar hyperkeratosis Hypertyrosinemia keratitis zone of skin liver