has material basis in autosomal dominant primary microcephaly 27 DOID:0051038 disease_ontology A primary microcephaly that is characterized by small head circumference apparent in early childhood and associated with global developmental delay manifest as delayed walking, inability to walk, impaired intellectual development, and poor or absent speech and that has_material_basis_in heterozygous mutation in the LMNB2 gene on chromosome 19p13. MIM:619180 autosomal dominant primary microcephaly autosomal dominant inheritance