NCIthesaurus coarctation of the aorta MIM:120000 MESH:D001017 A congenital heart disease that is characterized by the luminal narrowing of the thoracic aortic arch, typically located just beyond the left subclavian artery. This narrowing creates an obstruction that can lead to significant cardiovascular complications, including systemic hypertension, left ventricular hypertrophy, and eventually heart failure. NCI:C84567 disease_ontology DOID:0051054 congenital heart disease