has material basis in autosomal dominant disease Fontaine progeroid syndrome A progeroid syndrome that is characterized by poor growth, abnormal skeletal features, and distinctive craniofacial features with sagging, thin skin, and decreased subcutaneous fat suggesting an aged appearance that is most pronounced in infancy and improves with time and that has_material_basis_in heterozygous mutation in the SLC25A24 gene on chromosome 1p36. Gorlin-Chaudhry-Moss syndrome ORDO:2963 disease_ontology ORDO:2095 DOID:0051067 MIM:612289 ORDO:697101 Progeroid Syndrome, Congenital, Petty Type progeroid syndrome autosomal dominant inheritance