DO_rare_slim has symptom Omenn syndrome GARD:8198 DOID:0060010 A severe combined immunodeficiency that has_material_basis_in the RAG1 and RAG2 genes on chromosome 11p and the Artemis gene on chromosome 10p. It is characterized by erythroderma, desquamation, alopecia, chronic diarrhea, failure to thrive, lymphadenopathy, and hepatosplenomegaly. disease_ontology ICD10CM:D81.8 MIM:603554 combined immunodeficiency with hypereosinophilia severe combined immunodeficiency hepatosplenomegaly diarrhea