DO_rare_slim type II complement component 8 deficiency ORDO:169150 2015-02-09T15:32:25Z A complement deficiency that is characterized by deficiency of the beta subunit of complement protein 8, which causes increased susceptibility to recurrent bacterial infections, especially to Neisseria meningitidis, and has_material_basis_in autosomal recessive inheritance of mutation in the C8B gene, which produces the beta subunit of complement component 8 important in forming membrane attack complexes. MIM:613789 ICD10CM:D84.1 DOID:0060302 NT MGI. disease_ontology complement deficiency