DO_rare_slim has material basis in granular corneal dystrophy 2 disease_ontology An corneal granular dystrophy that is characterized by recurrent erosions and stellate or thorn-like opacification located_in the cornea, hyaline and amyloid deposits in the stroma, and progressive vision loss later in life, and has_material_basis_in autosomal dominant inheritance of mutation of transforming growth factor beta-induced gene on chromosome 5q31.1, which encodes keratoepithelin. Abnormalities lead to increased hyaline and amyloid protein deposition and disruption of the corneal surface. MESH:C535474 ORDO:98963 UMLS_CUI:C1275685 DOID:0060444 2015-10-16T16:44:27Z CGD2 MIM:607541 SNOMEDCT_US_2025_09_01:397568004 avellino corneal dystrophy combined granular-lattice corneal dystrophy corneal dystrophy, Avellino type granular corneal dystrophy type 2 granular corneal dystrophy autosomal dominant inheritance