has material basis in existence starts during autosomal dominant disease myoclonic-atonic epilepsy DOID:0060475 2015-11-19T16:30:12Z An idiopathic generalized epilepsy characterized by onset of multiple seizure types in the first few years of life and associated with poor prognosis. Affected individuals have cognitive regression and intellectual disability and that has_material_basis_in heterozygous mutation in the SLC6A1 gene on chromosome 3p25. disease_ontology MIM:616421 EEOC childhood onset epileptic encephalopathy generalized epilepsy autosomal dominant inheritance Childhood onset