has material basis in autosomal recessive disease complex cortical dysplasia with other brain malformations 10 CDCBM10 DOID:0061143 MIM:618677 disease_ontology A complex cortical dysplasia with other brain malformations characterized by severely impaired global development associated with abnormalities on brain imaging, including lissencephaly, cortical dysplasia, subcortical heterotopia, and paucity of white matter that has_material_basis_in homozygous or compound heterozygous mutation in the APC2 gene on chromosome 19p13. complex cortical dysplasia with other brain malformations autosomal recessive inheritance