has material basis in Stargardt disease Stargardt disease 4 claudiasbj A stargardt disease that is characterized by decreased central vision, atrophy of the macula and underlying retinal pigment epithelium, and frequent presence of prominent flecks in the posterior pole of the retina and has_material_basis_in heterozygous mutation in the prominin-1 gene on chromosome 4p15. disease_ontology DOID:0061239 MIM:603786 autosomal dominant inheritance