has material basis in autosomal recessive disease multiple mitochondrial dysfunctions syndrome multiple mitochondrial dysfunctions syndrome 6 MIM:617954 disease_ontology DOID:0070332 A multiple mitochondrial dysfunctions syndrome that is characterized by hypotonia, inability to walk, poor speech, intellectual disability, and motor abnormalities, such as ataxia, dystonia, and spasticity with onset in early childhood and has_material_basis_in autosomal recessive homozygous or compound heterozygous mutation in the PMPCB gene on chromosome 7q22. autosomal recessive inheritance