DO_rare_slim leukoencephalopathy with vanishing white matter leukoencephalopathy with vanishing white matter 5 'Cree leukoencephalopathy' synonym included in this subtype because of genetic link. The severity of this disease remains variable [JAB]. MIM:620315 ORDO:99854 A leukoencephalopathy with vanishing white matter that has_material_basis_in homozygous or compound heterozygous mutation in the EIF2B5 gene on chromosome 3q27. Cree leukoencephalopathy ORDO:99854 MIM:620315 DOID:0070367 disease_ontology