has material basis in X-linked spermatogenic failure 7 A spermatogenic failure characterized by sperm with insufficient individualization, excessive residual cytoplasm, acrosome defects, and abnormalities of the head and flagella, resulting in significantly reduced sperm concentration and progressive motility, that has_material_basis_in hemizygous mutation in the CT55 gene on chromosome Xq26.3. MIM:301106 DOID:0070598 disease_ontology MIM:301106 Only 1 family reported as of 2024-08-21. SPGFX7 X-linked recessive disease spermatogenic failure X-linked recessive inheritance