has material basis in autosomal recessive disease developmental and epileptic encephalopathy 55 DOID:0080283 A developmental and epileptic encephalopathy characterized by onset in the first weeks or months of life of refractory seizures, profoundly impaired intellectual development, absent speech, spastic quadriplegia, and dyskinetic movements that has_material_basis_in homozygous or compound heterozygous mutation in the PIGP gene on chromosome 21q22. DEE55 GPIBD14 MIM:617599 disease_ontology early infantile epileptic encephalopathy 55 glycosylphosphatidylinositol biosynthesis defect 14 developmental and epileptic encephalopathy autosomal recessive inheritance