has material basis in orofacial cleft autosomal recessive disease orofacial cleft 14 DOID:0080407 disease_ontology MIM:615892 An orofacial cleft that is characterized by incomplete median clefts of both the lower lip and upper lip, double labial frenulum and fusion of the upper gingival and upper labial mucosa, in addition to poor dental alignment, and increased interdental distance between the lower and upper median incisors. autosomal recessive inheritance