has material basis in autosomal dominant disease developmental and epileptic encephalopathy 41 A developmental and epileptic encephalopathy characterized by onset in the first days or weeks of life of seizures, severely impaired psychomotor development, and brain anomalies including delayed myelination, thin corpus callosum, and cerebral atrophy that has_material_basis_in heterozygous mutation in the SLC1A2 gene on chromosome 11p13. DOID:0080442 MIM:617105 disease_ontology DEE41 early infantile epileptic encephalopathy 41 developmental and epileptic encephalopathy autosomal dominant inheritance