NCIthesaurus hyper IgM syndrome MESH:D053306 UMLS_CUI:C0272236 disease_ontology NCI:C3990 MESH:D053306 A hyperimmunoglobin syndrome that is characterized by an immune system that fails to produce normal levels of the antibodies IgA, IgG and IgE but can produce normal or elevated levels of IgM. NCI:C3990 MIM:PS308230 SNOMEDCT_US_2025_09_01:82286005 ICD10CM:D80.5 DOID:0080544 HIGM MIM:PS308230 UMLS_CUI:C0272236 hyperimmunoglobulin M syndrome immunodeficiency with hyper-IgM hyperimmunoglobulin syndrome