metabolic dysfunction-associated steatotic liver disease obsolete non-alcoholic fatty liver true A metabolic dysfunction-associated steatotic liver disease characterized by the absence of inflammation and hepatocyte injury in the form of hepatocyte ballooning. DOID:0080546 NAFL NAFL was not addressed in the 2023 international update that revised the nomenclature and definition of NAFLD/MASLD and NASH/MASH. It has historically been considered a subtype of NAFLD/MASLD, but has frequently been used in clinical literature as a synonym for NAFLD itself. Use of NAFL in clinical literature has declined in connection with the decline of NAFLD. It no longer appears to represent a distinct disease entity (2024-11-22, JAB). disease_ontology nonalcoholic fatty liver