DO_cancer_slim NCIthesaurus diffuse large B-cell lymphoma MCD diffuse large B-cell lymphoma A diffuse large B-cell lymphoma that is categorized as MCD with high probability by the LymphGen algorithm. This is based on a combination of genetic features and MCD DLBCLs often, but do not always, have the most common hot spot mutation in MYD88 (L265P) and/or activating mutations in CD79B. This subgroup also commonly has mutations due to aberrant somatic hypermutation affecting PIM1 and/or ETV6, which can be coding or non-coding. NCI:C148394 DOID:0081066 MCD DLBCL disease_ontology