has material basis in autosomal dominant disease LADD syndrome lacrimoauriculodentodigital syndrome 2 disease_ontology DOID:0081371 A LADD syndrome that has_material_basis_in heterozygous mutation in the tyrosine kinase domain of the FGFR3 gene on chromosome 4p16 and that is mainly affecting lacrimal glands and ducts, salivary glands and ducts, ears, teeth, and distal limb segments. Lacrimo-auriculo-dento-digital syndrome 2 MIM:620192 autosomal dominant inheritance