has material basis in disease has basis in Axenfeld-Rieger syndrome type 3 ICD10CM:Q13.8 DOID:0110122 MIM:602482 An Axenfeld-Rieger characterized by an anteriorly displaced Schwalbe line, the presence of another ocular anomaly (hypoplasia of iris stroma, corectopia, or iridocorneal adhesions), and nonocular anomalies including maxillary hypoplasia, hypodontia, microdontia, protuberant periumbilical skin, sensorineural hearing loss, and congenital cardiac or renal anomalies syndrome that has_material_basis_in heterozygous mutation in the FOXC1 gene on chromosome 6p25. RIEG3 Rieger syndrome type 3 anterior chamber cleavage syndrome anterior segment mesenchymal dysgenesis disease_ontology Axenfeld-Rieger anomaly with or without cardiac defects and/or sensorineural hearing loss Axenfeld-Rieger syndrome autosomal dominant inheritance structural_variant