has material basis in has symptom disease has basis in autosomal dominant disease physical disorder developmental and epileptic encephalopathy 117 disease_ontology A developmental and epileptic encephalopathy that is characterized by global developmental delay, hypotonia, delayed walking or inability to walk, and variably impaired intellectual development with poor or absent speech and that has_material_basis_in heterozygous mutation in the SNAP25 gene on chromosome 20p11. DEE117 MIM:616330 DOID:0110683 CMS18 congenital myasthenic syndrome 18 developmental and epileptic encephalopathy autosomal dominant inheritance Abnormality of prenatal development or birth muscle weakness