DO_rare_slim amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 ORDO:90020 ALS-PDC UMLS_CUI:C0543859 disease_ontology GARD:9239 MIM:105500 A neurodegenerative disease characterized by chronic, progressive amyotrophic lateral sclerosis and parkinsonism-dementia. Susceptibility to this disease is influenced by heterozygous mutation in TRPM7 on 15q21.2. Amyotrophic lateral sclerosis-parkinsonism-dementia of Guam syndrome Guam disease MESH:D000690 Lytico-Bodig disease PDALS SNOMEDCT_US_2025_09_01:62239001 DOID:0111246 amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam parkinsonism-dementia-ALS complex neurodegenerative disease