DO_rare_slim has material basis in autosomal dominant disease bone remodeling disease familial expansile osteolysis GARD:9168 DOID:0111542 McCabe disease SNOMEDCT_US_2025_09_01:254153009 FEO UMLS_CUI:C0432292 disease_ontology ORDO:85195 A bone remodeling disease characterized by increased bone remodeling with osteolytic lesions mainly affecting the appendicular skeleton, bone pain, pathological fractures, childhood onset of conductive hearing loss, and premature tooth loss that has_material_basis_in heterozygous mutation in the TNFRSF11A gene on chromosome 18q21.33. MESH:C536335 MIM:174810 hereditary expansile polyostotic osteolytic dysplasia autosomal dominant inheritance