DO_rare_slim ACTH-independent macronodular adrenal hyperplasia UMLS_CUI:C2062388 ORDO:189427 A primary hyperaldosteronism characterized by multiple bilateral adrenocortical nodules that cause a striking enlargement of the adrenal gland and production of an excess of cortisol. disease_ontology GARD:10824 ACTH-independent macronodular adrenocortical hyperplasia DOID:0111622 SNOMEDCT_US_2025_09_01:720459002 AIMAH Cushing syndrome due to macronodular adrenal hyperplasia MMAD adrenocorticotropic hormone-independent macronodular adrenal hyperplasia corticotropin-independent macronodular adrenal hyperplasia massive macronodular adrenocortical disease primary macronodular adrenal hyperplasia primary hyperaldosteronism