DO_rare_slim NCIthesaurus has material basis in autosomal dominant disease familial episodic pain syndrome familial episodic pain syndrome 3 DOID:0111731 A familial episodic pain syndrome characterized by early childhood onset of intense episodic pain mainly affecting the distal lower extremities, but sometimes also the upper extremities, with pain cycles lasting several days and exacerbated by fatigue that has_material_basis_in heterozygous mutation in the SCN11A gene on chromosome 3p22. MIM:615552 FEPS3 ORDO:391392 NCI:C125390 disease_ontology autosomal dominant inheritance