DO_rare_slim has material basis in X-linked monogenic disease otopalatodigital syndrome spectrum disorder Melnick-Needles syndrome SNOMEDCT_US_2025_09_01:13449007 An otopalatodigital syndrome spectrum disorder characterized by short stature, facial dysmorphism, osseous abnormalities involving the majority of the axial and appendicular skeleton resulting in impaired speech and masticatory problems that has_material_basis_in heterozygous or hemizygous mutation in the FLNA gene on chromosome Xq28. UMLS_CUI:C0025237 disease_ontology GARD:7011 DOID:0111788 MIM:309350 MESH:D010009 MEDDRA:10060908 MNS Melnick-Needles osteodysplasty ORDO:1826 osteodysplasty of Melnick and Needles X-linked inheritance