NCIthesaurus has material basis in autosomal dominant disease immunodeficiency 11B DOID:0111958 disease_ontology A T cell deficiency characterized by defects in T-cell activation, increased IgE, eosinophilia and early childhood onset of moderate to severe atopic dermatitis that has_material_basis_in heterozygous mutation in the CARD11 gene on chromosome 7p22.2. NCI:C176630 MIM:617638 UMLS_CUI:C4539957 IMD11B atopic dermatitis, elevated IgE, and eosinophilia immunodeficiency 11B with atopic dermatitis T cell deficiency autosomal dominant inheritance