DO_rare_slim NCIthesaurus has material basis in autosomal recessive disease T cell and NK cell immunodeficiency immunodeficiency 30 A T cell and NK cell immunodeficiency characterized by absence of responses to IL12 and IL23 in T calls and NK cells that has_material_basis_in homozygous or compound heterozygous mutation in the IL12RB1 gene on chromosome 19p13.11. UMLS_CUI:C4013949 ORDO:319552 MIM:614891 disease_ontology DOID:0111990 IMD30 MSMD due to complete IL12RB1 deficiency MSMD due to complete interleukin 12 receptor beta 1 deficiency Mendelian susceptibility to interleukin 12 receptor beta 1 deficiency Mendelian susceptibility to mycobacterial diseases due to complete IL12RB1 deficiency NCI:C176800 autosomal recessive inheritance