has material basis in autosomal recessive disease developmental and epileptic encephalopathy developmental and epileptic encephalopathy 86 MIM:618910 A developmental and epileptic encephalopathy characterized by severe and persistent seizures associated with EEG abnormalities beginning in the first few months of life, global developmental delay, severe motor deficits, dystonic movements, and dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the DALRD2 gene on chromosome 3p21.31. DEE86 disease_ontology DOID:0112220 early infantile epileptic encephalopathy 86 autosomal recessive inheritance