zoonotic_infectious_disease obsolete Trypanosoma brucei rhodesiense infectious disease true DOID:10114 disease_ontology A sleeping sickness that involves infection caused by Trypanosoma brucei rhodesiense, which is carried by the tsetse fly. The symptoms include fever, severe headache, irritability, extreme fatigue, swollen lymph nodes, aching muscles and joints, skin rash, progressive confusion, personality changes, and other neurologic problems. East African trypanosomiasis Rhodesian sleeping sickness Rhodesian trypanosomiasis trypanosoma rhodesiense infectious disease