DO_rare_slim NCIthesaurus familial periodic paralysis UMLS_CUI:C0030443 disease_ontology NCI:C84709 GARD:6422 DOID:1029 ICD10CM:G72.3 SNOMEDCT_US_2025_09_01:193241004 MESH:D010245 A metal metabolism disorder that is characterized by episodes of muscle paralysis in which the affected muscles become flaccid and the deep tendon reflexes disappear. Between the episodes the affected muscles usually work normally, and that are caused by mutations in genes involved in the sodium and calcium channels in nerve cells. metal metabolism disorder