DO_rare_slim DO_RAD_slim NCIthesaurus Alzheimer's disease GARD:10254 MESH:D000544 A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid. ICD9CM:331.0 UMLS_CUI:C0002395 Alzheimers dementia SNOMEDCT_US_2025_09_01:73768007 DOID:10652 Alzheimer disease NCI:C2866 disease_ontology ICD10CM:G30 KEGG:05010 Xref MGI. OMIM mapping confirmed by DO. [SN]. tauopathy