has symptom disease has feature buphthalmos SNOMEDCT_US_2025_09_01:204116009 A hydrophthalmos characterized by early onset glaucoma in one or both eyes with elevated intraocular pressure, increased corneal diameter, and swelling of the globe and has_symptom early vision loss, photophobia, blepharospasm, tearing, increased corneal diameter, increased corneal thickness, and enlarged globe. Buphthalmos is caused by severe congenital defects of the trabecular meshwork and anterior chamber angle that block aqueous outflow and raises intraocular pressure, leading to optic nerve atrophy and early vision loss. MIM:231300 UMLS_CUI:C0311251 ICD9CM:743.21 disease_ontology DOID:11211 OMIM mapping confirmed by DO. [LS]. primary congenital glaucoma 3A simple buphthalmos hydrophthalmos blepharospasm ocular hypertension photophobia