NCIthesaurus disease has feature primary congenital glaucoma hydrophthalmos MESH:D006871 UMLS_CUI:C0020302 ICD10CM:Q15.0 DOID:11212 disease_ontology SNOMEDCT_US_2025_09_01:392368005 NCI:C50648 A primary congenital glaucoma characterized by early onset glaucoma in one or both eyes with elevated intraocular pressure and increased corneal diameter and has_symptom early vision loss, increased corneal diameter, and increased corneal thickness. Hydrophthalmus is caused by congenital defects of the trabecular meshwork and anterior chamber angle that block aqueous outflow and raises intraocular pressure, leading to optic nerve atrophy and early vision loss. ocular hypertension