DO_infectious_disease_slim DO_rare_slim zoonotic_infectious_disease NCIthesaurus has material basis in has symptom trypanosomiasis Chagas disease DOID:0050016 MESH:D014355 DOID:0050019 American trypanosomiasis ORDO:3386 NCI:C84629 disease_ontology UMLS_CUI:C0041234 DOID:0050020 A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis. Chagas' disease GARD:6030 SNOMEDCT_US_2025_09_01:77506005 DOID:12140 ICD10CM:B57 KEGG:05142 chagas' disease with digestive system involvement chagas' disease with nervous system involvement chagas' disease with other organ involvement Trypanosoma cruzi myocarditis body ache loss of appetite rash headache diarrhea fever vomiting fatigue