gram-positive_bacterial_infectious_disease DO_infectious_disease_slim NCIthesaurus has material basis in has phenotype has symptom commensal bacterial infectious disease toxic shock syndrome UMLS_CUI:C0600327 MESH:D012772 NCI:C35498 SNOMEDCT_US_2025_09_01:18504008 ICD9CM:040.82 disease_ontology A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities. ICD10CM:A48.3 DOID:14115 TSS toxic shock Abnormality of the nervous system Staphylococcus aureus Streptococcus pyogenes hypotension shock rash headache diarrhea fever skin desquamation vomiting