DO_rare_slim NCIthesaurus has major susceptibility factor disease has location autoimmune disease of central nervous system multiple sclerosis GARD:10255 DOID:2377 MIM:612594 ICD9CM:340 ICD10CM:G35 Generalized multiple sclerosis MIM:612595 MIM:612596 UMLS_CUI:C0026769 SNOMEDCT_US_2025_09_01:155023009 MESH:D009103 NCI:C3243 MESH:D009103 OMIM mapping confirmed by DO. [LS]. disease_ontology A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring. insular sclerosis demyelinating disease autoimmune disease susceptibility to multiple sclerosis susceptibility to multiple sclerosis 5 central nervous system