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        <rdfs:label xml:lang="en">has phenotype</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_2571 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_2571">
        <rdfs:label xml:lang="en">Langerhans-cell histiocytosis</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_3405"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002200"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/HP_0006530"/>
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        <oboInOwl:hasDbXref>ICD10CM:C96.6</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2025_09_01:154583006</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:C96.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3160</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>DOID:10623</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10625</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10624</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>UMLS_CUI:C0019621</oboInOwl:hasDbXref>
        <oboInOwl:id>DOID:2571</oboInOwl:id>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2025_09_01:234439008</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD9CM:202.5</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C3107</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:604856</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:246400</oboInOwl:hasDbXref>
        <ns4:IAO_0000115 xml:lang="en">A histiocytosis that is characterized by clonal proliferation of Langerhans cells.</ns4:IAO_0000115>
        <oboInOwl:hasDbXref>ICDO:9751/1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0023381</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>DOID:10620</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2554</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:2553</oboInOwl:hasAlternativeId>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasAlternativeId>DOID:9582</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>MESH:D006646</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>DOID:10618</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId>DOID:10617</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym xml:lang="en">Histiocytosis X</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Langerhan&#39;s cell histiocytosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Langerhans cell granulomatosis</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving intra-abdominal lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving intrapelvic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving intrathoracic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving lymph nodes of axilla and upper limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving lymph nodes of head, face and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving lymph nodes of head, face, and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving lymph nodes of inguinal region and lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving lymph nodes of multiple sites</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease involving spleen</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of intra-abdominal lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of intrapelvic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of intrathoracic lymph nodes</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of axilla and upper limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of axilla and/or upper limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of head, face and neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of head, face and/or neck</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of inguinal region amd/or lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of inguinal region and lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of lymph nodes of multiple sites</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">Letterer-Siwe disease of spleen</oboInOwl:hasExactSynonym>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/doid#DO_cancer_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/doid#NCIthesaurus"/>
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        <rdfs:label xml:lang="en">histiocytosis</rdfs:label>
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    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0006530">
        <rdfs:label>Abnormal pulmonary interstitial morphology</rdfs:label>
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