DO_rare_slim NCIthesaurus has phenotype has symptom has major susceptibility factor bronchial disease asthma KEGG:05310 ICD9CM:493 disease_ontology DOID:13830 SNOMEDCT_US_2025_09_01:187687003 DOID:2840 DOID:12703 NCI:C28397 A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing. DOID:2841 MESH:D001249 MIM:600807 MESH:D001249 ICD10CM:J45 UMLS_CUI:C0004096 DOID:5783 DOID:13829 GARD:10246 Xref MGI. bronchial hyperreactivity chronic obstructive asthma chronic obstructive asthma with acute exacerbation chronic obstructive asthma with status asthmaticus Abnormal respiratory system physiology susceptibility to asthma inflammation wheezing cough dyspnea airway stenosis chronic inflammation chest tightness