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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/doid#DO_RAD_slim">
        <rdfs:label>DO_RAD_slim</rdfs:label>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/RO_0004026 -->

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        <rdfs:label>disease has location</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_114 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_114">
        <rdfs:label xml:lang="en">heart disease</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_4079 -->

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        <rdfs:label xml:lang="en">heart valve disease</rdfs:label>
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        <oboInOwl:hasAlternativeId>DOID:989</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>MESH:D006349</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C45525</oboInOwl:hasDbXref>
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        <oboInOwl:hasDbXref>SNOMEDCT_US_2025_09_01:368009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D016127</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0018824</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C0079485</oboInOwl:hasDbXref>
        <ns4:IAO_0000115 xml:lang="en">A heart disease involving one or more of the four valves of the heart (the aortic and mitral valves on the left and the pulmonary and tricuspid valves on the right).</ns4:IAO_0000115>
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    <!-- http://purl.obolibrary.org/obo/UBERON_0000946 -->

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        <rdfs:label>cardiac valve</rdfs:label>
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