<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/DOID?iri=http://purl.obolibrary.org/obo/DOID_437"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:doid="http://purl.obolibrary.org/obo/doid#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasOBONamespace"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/doid#DO_rare_slim">
        <rdfs:label>DO_rare_slim</rdfs:label>
    </AnnotationProperty>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasAlternativeId"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/doid#NCIthesaurus">
        <rdfs:label>NCIthesaurus</rdfs:label>
    </AnnotationProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0002452 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002452">
        <rdfs:label>has symptom</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/DOID_437 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_437">
        <rdfs:label xml:lang="en">myasthenia gravis</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_438"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002452"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SYMP_0000094"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002452"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SYMP_0000414"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002452"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SYMP_0000493"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002452"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SYMP_0019153"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002452"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SYMP_0000369"/>
            </Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002452"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/SYMP_0000258"/>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:hasDbXref>UMLS_CUI:C0026896</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>DOID:444</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>GARD:7122</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId>DOID:443</oboInOwl:hasAlternativeId>
        <oboInOwl:hasDbXref>ICD10CM:G70.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIM:254200</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:G70.00</oboInOwl:hasDbXref>
        <ns4:IAO_0000115 xml:lang="en">An autoimmune disease of the nervous system that has_material_basis_in antibodies to acetylcholine receptors at the neuromuscular junction, has_symptom ptosis, has_symptom diplopia, has_symptom dysphagia, has_symptom dysarthria, has_symptom muscle weakness and has_symptom shortness of breath.</ns4:IAO_0000115>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>ICD9CM:358.00</oboInOwl:hasDbXref>
        <oboInOwl:id>DOID:437</oboInOwl:id>
        <oboInOwl:hasDbXref>ICD9CM:358.0</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D009157</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>NCI:C60989</oboInOwl:hasDbXref>
        <rdfs:comment xml:lang="en">OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2025_09_01:155092009</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS_CUI:C1260409</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/doid#DO_rare_slim"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/doid#NCIthesaurus"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/DOID_438 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_438">
        <rdfs:label xml:lang="en">autoimmune disease of the nervous system</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SYMP_0000094 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SYMP_0000094">
        <rdfs:label>muscle weakness</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SYMP_0000258 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SYMP_0000258">
        <rdfs:label>double vision</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SYMP_0000369 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SYMP_0000369">
        <rdfs:label>ptosis</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SYMP_0000414 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SYMP_0000414">
        <rdfs:label>dysarthria</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SYMP_0000493 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SYMP_0000493">
        <rdfs:label>dysphagia</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SYMP_0019153 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SYMP_0019153">
        <rdfs:label>dyspnea</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



