DO_infectious_disease_slim zoonotic_infectious_disease NCIthesaurus has material basis in transmitted by has symptom human immunodeficiency virus infectious disease disease_ontology MESH:D015658 DOID:526 HIV infection UMLS_CUI:C0019693 SNOMEDCT_US_2025_09_01:86406008 ICD9CM:042-042.99 NCI:C3108 A viral infectious disease that results in destruction of immune system, leading to life-threatening opportunistic infections and cancers, has_material_basis_in Human immunodeficiency virus 1 (Lentivirus humimdef1) or Human immunodeficiency virus 2 (Lentivirus humimdef2), which are transmitted by sexual contact, transmitted by transfer of blood, semen, vaginal fluid, pre-ejaculate, or breast milk, transmitted by congenital method, and transmitted by contaminated needles. The virus infects helper T cells (CD4+ T cells) which are directly or indirectly destroyed, macrophages, and dendritic cells. The infection has symptom diarrhea, has symptom fatigue, has symptom fever, has symptom vaginal yeast infection, has symptom headache, has symptom mouth sores, has symptom muscle aches, has symptom sore throat, and has symptom swollen lymph glands. ICD10CM:B20 viral infectious disease Human immunodeficiency virus Lentivirus humimdef1 Lentivirus humimdef2 headache diarrhea fever lymphadenitis fatigue apthous ulcer pharynx inflammation congenital transmission contact transmission vehicle-borne fomite transmission vehicle-borne ingestion transmission vehicle-borne medical transmission